The Role of the 3′UTR Region in the Regulation of the ACVR1/Alk-2 Gene Expression

BACKGROUND: The ACVR1/Alk-2 gene, encoding a BMP type I receptor, is mutated in Fibrodysplasia Ossificans Progressiva, a severe form of heterotopic ossification. Regulation of ACVR1/Alk-2 expression, still poorly understood, is likely to be controlled by transcriptional and post-transcriptional mech...

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Detalles Bibliográficos
Autores principales: Mura, Marzia, Cappato, Serena, Giacopelli, Francesca, Ravazzolo, Roberto, Bocciardi, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515447/
https://www.ncbi.nlm.nih.gov/pubmed/23227223
http://dx.doi.org/10.1371/journal.pone.0050958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515447/
https://www.ncbi.nlm.nih.gov/pubmed/23227223
http://dx.doi.org/10.1371/journal.pone.0050958

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