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Acetyl-L-Carnitine Improves Behavior and Dendritic Morphology in a Mouse Model of Rett Syndrome

Rett syndrome (RTT) is a devastating neurodevelopmental disorder affecting 1 in 10,000 girls. Approximately 90% of cases are caused by spontaneous mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MeCP2). Girls with RTT suffer from severe motor, respiratory, cognitive and social...

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Detalles Bibliográficos
Autores principales: Schaevitz, Laura R., Nicolai, Raffaella, Lopez, Carla M., D'Iddio, Stefania, Iannoni, Emerenziana, Berger-Sweeney, Joanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515484/
https://www.ncbi.nlm.nih.gov/pubmed/23227269
http://dx.doi.org/10.1371/journal.pone.0051586