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Acetyl-L-Carnitine Improves Behavior and Dendritic Morphology in a Mouse Model of Rett Syndrome
Rett syndrome (RTT) is a devastating neurodevelopmental disorder affecting 1 in 10,000 girls. Approximately 90% of cases are caused by spontaneous mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MeCP2). Girls with RTT suffer from severe motor, respiratory, cognitive and social...
Autores principales: | Schaevitz, Laura R., Nicolai, Raffaella, Lopez, Carla M., D'Iddio, Stefania, Iannoni, Emerenziana, Berger-Sweeney, Joanne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515484/ https://www.ncbi.nlm.nih.gov/pubmed/23227269 http://dx.doi.org/10.1371/journal.pone.0051586 |
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