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Systemic Analysis of Gene Expression Profiles Identifies ErbB3 as a Potential Drug Target in Pediatric Alveolar Rhabdomyosarcoma

Pediatric sarcomas, including rhabdomyosarcomas, Ewing’s sarcoma, and osteosarcoma, are aggressive tumors with poor survival rates. To overcome problems associated with nonselectivity of the current therapeutic approaches, targeted therapeutics have been developed. Currently, an increasing number of...

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Detalles Bibliográficos
Autores principales: Nordberg, Janne, Mpindi, John Patrick, Iljin, Kristiina, Pulliainen, Arto Tapio, Kallajoki, Markku, Kallioniemi, Olli, Elenius, Klaus, Elenius, Varpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515522/
https://www.ncbi.nlm.nih.gov/pubmed/23227212
http://dx.doi.org/10.1371/journal.pone.0050819