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Nucleosome spacing and chromatin higher-order folding
Packing of about two meters of the human genome DNA into chromatin occupying a several micron-sized cell nucleus requires a high degree of compaction in a manner that allows the information encoded on DNA to remain easily accessible. This packing is mediated by repeated coiling of DNA double helix a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515531/ https://www.ncbi.nlm.nih.gov/pubmed/22990522 http://dx.doi.org/10.4161/nucl.22168 |