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Nucleosome spacing and chromatin higher-order folding

Packing of about two meters of the human genome DNA into chromatin occupying a several micron-sized cell nucleus requires a high degree of compaction in a manner that allows the information encoded on DNA to remain easily accessible. This packing is mediated by repeated coiling of DNA double helix a...

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Detalles Bibliográficos
Autor principal: Grigoryev, Sergei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515531/
https://www.ncbi.nlm.nih.gov/pubmed/22990522
http://dx.doi.org/10.4161/nucl.22168