Cargando…

Macrophages Facilitate Coal Tar Pitch Extract-Induced Tumorigenic Transformation of Human Bronchial Epithelial Cells Mediated by NF-κB

OBJECTIVE: Chronic respiratory inflammation has been associated with lung cancer. Tumor-associated macrophages (TAMs) play a critical role in the formation of inflammation microenvironment. We sought to characterize the role of TAMs in coal tar pitch extract (CTPE)-induced tumorigenic transformation...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Feifei, Wu, Yiming, Zhang, Shaofeng, Liu, Yu, Qin, Lijuan, Wu, Yongjun, Yan, Zhen, Wu, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515562/
https://www.ncbi.nlm.nih.gov/pubmed/23227270
http://dx.doi.org/10.1371/journal.pone.0051690