Structural Dynamics of Troponin I during Ca2+-Activation of Cardiac Thin Filaments: A Multi-Site Förster Resonance Energy Transfer Study

A multi-site, steady-state Förster resonance energy transfer (FRET) approach was used to quantify Ca(2+)-induced changes in proximity between donor loci on human cardiac troponin I (cTnI), and acceptor loci on human cardiac tropomyosin (cTm) and F-actin within functional thin filaments. A fluorescen...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Chalovich, Joseph M., Marriott, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515578/
https://www.ncbi.nlm.nih.gov/pubmed/23227172
http://dx.doi.org/10.1371/journal.pone.0050420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515578/
https://www.ncbi.nlm.nih.gov/pubmed/23227172
http://dx.doi.org/10.1371/journal.pone.0050420

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