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Plasmodium falciparum Rosetting Epitopes Converge in the SD3-Loop of PfEMP1-DBL1α

The ability of Plasmodium falciparum parasitized RBC (pRBC) to form rosettes with normal RBC is linked to the virulence of the parasite and RBC polymorphisms that weaken rosetting confer protection against severe malaria. The adhesin PfEMP1 mediates the binding and specific antibodies prevent seques...

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Detalles Bibliográficos
Autores principales: Angeletti, Davide, Albrecht, Letusa, Blomqvist, Karin, Quintana, María del Pilar, Akhter, Tahmina, Bächle, Susanna M., Sawyer, Alan, Sandalova, Tatyana, Achour, Adnane, Wahlgren, Mats, Moll, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515580/
https://www.ncbi.nlm.nih.gov/pubmed/23227205
http://dx.doi.org/10.1371/journal.pone.0050758