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Plasmodium falciparum Rosetting Epitopes Converge in the SD3-Loop of PfEMP1-DBL1α
The ability of Plasmodium falciparum parasitized RBC (pRBC) to form rosettes with normal RBC is linked to the virulence of the parasite and RBC polymorphisms that weaken rosetting confer protection against severe malaria. The adhesin PfEMP1 mediates the binding and specific antibodies prevent seques...
Autores principales: | Angeletti, Davide, Albrecht, Letusa, Blomqvist, Karin, Quintana, María del Pilar, Akhter, Tahmina, Bächle, Susanna M., Sawyer, Alan, Sandalova, Tatyana, Achour, Adnane, Wahlgren, Mats, Moll, Kirsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515580/ https://www.ncbi.nlm.nih.gov/pubmed/23227205 http://dx.doi.org/10.1371/journal.pone.0050758 |
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