MDA5 Can Be Exploited as Efficacious Genetic Adjuvant for DNA Vaccination against Lethal H5N1 Influenza Virus Infection in Chickens

Chickens lack the retinoic acid-inducible gene I (RIG-I) and sense avian influenza virus (AIV) infections by means of the melanoma differentiation-associated gene 5 product (chMDA5). Plasmid-driven expression of the N-terminal half of chMDA5 containing the caspase activation and recruitment domains...

Descripción completa

Detalles Bibliográficos
Autores principales: Liniger, Matthias, Summerfield, Artur, Ruggli, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515599/
https://www.ncbi.nlm.nih.gov/pubmed/23227156
http://dx.doi.org/10.1371/journal.pone.0049952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515599/
https://www.ncbi.nlm.nih.gov/pubmed/23227156
http://dx.doi.org/10.1371/journal.pone.0049952

Ejemplares similares