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JNK Pathway Activation Is Controlled by Tao/TAOK3 to Modulate Ethanol Sensitivity

Neuronal signal transduction by the JNK MAP kinase pathway is altered by a broad array of stimuli including exposure to the widely abused drug ethanol, but the behavioral relevance and the regulation of JNK signaling is unclear. Here we demonstrate that JNK signaling functions downstream of the Ster...

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Detalles Bibliográficos
Autores principales: Kapfhamer, David, King, Ian, Zou, Mimi E., Lim, Jana P., Heberlein, Ulrike, Wolf, Fred W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515618/
https://www.ncbi.nlm.nih.gov/pubmed/23227189
http://dx.doi.org/10.1371/journal.pone.0050594