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Role of the Skp1 prolyl-hydroxylation/glycosylation pathway in oxygen dependent submerged development of Dictyostelium

BACKGROUND: Oxygen sensing is a near universal signaling modality that, in eukaryotes ranging from protists such as Dictyostelium and Toxoplasma to humans, involves a cytoplasmic prolyl 4-hydroxylase that utilizes oxygen and α-ketoglutarate as potentially rate-limiting substrates. A divergence betwe...

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Detalles Bibliográficos
Autores principales: Xu, Yuechi, Wang, Zhuo A, Green, Rebekah S, West, Christopher M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515798/
https://www.ncbi.nlm.nih.gov/pubmed/23098648
http://dx.doi.org/10.1186/1471-213X-12-31