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Association between polymorphisms at N-acetyltransferase 1 (NAT1) & risk of oral leukoplakia & cancer

BACKGROUND & OBJECTIVES: N-acetyltransferases 1 and 2 (NAT1 and NAT2) are important enzymes for metabolism of tobacco carcinogens. Due to polymorphisms, improper activities of these enzymes might lead to the formation of DNA adducts that may modulate risk of tobacco related oral precancer and ca...

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Detalles Bibliográficos
Autores principales: Majumder, Mousumi, Ghosh, Saurabh, Roy, Bidyut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516028/
https://www.ncbi.nlm.nih.gov/pubmed/23168701