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Combined small molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

There has been considerable progress in identifying signaling pathways directing the differentiation of human pluripotent stem cells (hPSCs) into specialized cell types including neurons. However, extrinsic factor-based differentiation of hPSCs is a slow, step-wise process mimicking the protracted t...

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Detalles Bibliográficos
Autores principales: Chambers, Stuart M., Qi, Yuchen, Mica, Yvonne, Lee, Gabsang, Zhang, Xin-Jun, Niu, Lei, Bilsland, James, Cao, Lishuang, Stevens, Edward, Whiting, Paul, Shi, Song-Hai, Studer, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516136/
https://www.ncbi.nlm.nih.gov/pubmed/22750882
http://dx.doi.org/10.1038/nbt.2249