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Combined small molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors
There has been considerable progress in identifying signaling pathways directing the differentiation of human pluripotent stem cells (hPSCs) into specialized cell types including neurons. However, extrinsic factor-based differentiation of hPSCs is a slow, step-wise process mimicking the protracted t...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516136/ https://www.ncbi.nlm.nih.gov/pubmed/22750882 http://dx.doi.org/10.1038/nbt.2249 |