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Invariance (?) of Mutational Parameters for Relative Fitness Over 400 Generations of Mutation Accumulation in Caenorhabditis elegans

Evidence is accumulating that individuals in poor physiologic condition may accumulate mutational damage faster than individuals in good condition. If poor condition results from pre-existing deleterious mutations, the result is “fitness-dependent mutation rate,” which has interesting theoretical im...

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Detalles Bibliográficos
Autores principales: Matsuba, Chikako, Lewis, Suzanna, Ostrow, Dejerianne G., Salomon, Matthew P., Sylvestre, Laurence, Tabman, Brandon, Ungvari-Martin, Judit, Baer, Charles F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516472/
https://www.ncbi.nlm.nih.gov/pubmed/23275873
http://dx.doi.org/10.1534/g3.112.003947