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Invariance (?) of Mutational Parameters for Relative Fitness Over 400 Generations of Mutation Accumulation in Caenorhabditis elegans
Evidence is accumulating that individuals in poor physiologic condition may accumulate mutational damage faster than individuals in good condition. If poor condition results from pre-existing deleterious mutations, the result is “fitness-dependent mutation rate,” which has interesting theoretical im...
Autores principales: | Matsuba, Chikako, Lewis, Suzanna, Ostrow, Dejerianne G., Salomon, Matthew P., Sylvestre, Laurence, Tabman, Brandon, Ungvari-Martin, Judit, Baer, Charles F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516472/ https://www.ncbi.nlm.nih.gov/pubmed/23275873 http://dx.doi.org/10.1534/g3.112.003947 |
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