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A Targeted In Vivo RNAi Screen Reveals Deubiquitinases as New Regulators of Notch Signaling
Notch signaling is highly conserved in all metazoan animals and plays critical roles in cell fate specification, cell proliferation, apoptosis, and stem cell maintenance. Although core components of the Notch signaling cascade have been identified, many gaps in the understanding of the Notch signali...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516478/ https://www.ncbi.nlm.nih.gov/pubmed/23275879 http://dx.doi.org/10.1534/g3.112.003780 |