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In Vivo Regulation of E2F1 by Polycomb Group Genes in Drosophila

The E2F transcription factors are important regulators of the cell cycle whose function is commonly misregulated in cancer. To identify novel regulators of E2F1 activity in vivo, we used Drosophila to conduct genetic screens. For this, we generated transgenic lines that allow the tissue-specific dep...

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Detalles Bibliográficos
Autores principales: Ji, Jun-Yuan, Miles, Wayne O., Korenjak, Michael, Zheng, Yani, Dyson, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516486/
https://www.ncbi.nlm.nih.gov/pubmed/23275887
http://dx.doi.org/10.1534/g3.112.004333