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In Vivo Regulation of E2F1 by Polycomb Group Genes in Drosophila
The E2F transcription factors are important regulators of the cell cycle whose function is commonly misregulated in cancer. To identify novel regulators of E2F1 activity in vivo, we used Drosophila to conduct genetic screens. For this, we generated transgenic lines that allow the tissue-specific dep...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516486/ https://www.ncbi.nlm.nih.gov/pubmed/23275887 http://dx.doi.org/10.1534/g3.112.004333 |