A Novel Test for Gene-Ancestry Interactions in Genome-Wide Association Data

Genome-wide association study (GWAS) data on a disease are increasingly available from multiple related populations. In this scenario, meta-analyses can improve power to detect homogeneous genetic associations, but if there exist ancestry-specific effects, via interactions on genetic background or w...

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Detalles Bibliográficos
Autores principales: Davies, Joanna L., Cazier, Jean-Baptiste, Dunlop, Malcolm G., Houlston, Richard S., Tomlinson, Ian P., Holmes, Chris C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516524/
https://www.ncbi.nlm.nih.gov/pubmed/23236349
http://dx.doi.org/10.1371/journal.pone.0048687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516524/
https://www.ncbi.nlm.nih.gov/pubmed/23236349
http://dx.doi.org/10.1371/journal.pone.0048687

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