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A Novel Test for Gene-Ancestry Interactions in Genome-Wide Association Data
Genome-wide association study (GWAS) data on a disease are increasingly available from multiple related populations. In this scenario, meta-analyses can improve power to detect homogeneous genetic associations, but if there exist ancestry-specific effects, via interactions on genetic background or w...
Autores principales: | Davies, Joanna L., Cazier, Jean-Baptiste, Dunlop, Malcolm G., Houlston, Richard S., Tomlinson, Ian P., Holmes, Chris C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516524/ https://www.ncbi.nlm.nih.gov/pubmed/23236349 http://dx.doi.org/10.1371/journal.pone.0048687 |
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