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Genomic Hallmarks of Genes Involved in Chromosomal Translocations in Hematological Cancer
Reciprocal chromosomal translocations (RCTs) leading to the formation of fusion genes are important drivers of hematological cancers. Although the general requirements for breakage and fusion are fairly well understood, quantitative support for a general mechanism of RCT formation is still lacking....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516532/ https://www.ncbi.nlm.nih.gov/pubmed/23236267 http://dx.doi.org/10.1371/journal.pcbi.1002797 |