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Recurrent Targeted Genes of Hepatitis B Virus in the Liver Cancer Genomes Identified by a Next-Generation Sequencing–Based Approach

Integration of the viral DNA into host chromosomes was found in most of the hepatitis B virus (HBV)–related hepatocellular carcinomas (HCCs). Here we devised a massive anchored parallel sequencing (MAPS) method using next-generation sequencing to isolate and sequence HBV integrants. Applying MAPS to...

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Detalles Bibliográficos
Autores principales: Ding, Dong, Lou, Xiaoyan, Hua, Dasong, Yu, Wei, Li, Lisha, Wang, Jun, Gao, Feng, Zhao, Na, Ren, Guoping, Li, Lanjuan, Lin, Biaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516541/
https://www.ncbi.nlm.nih.gov/pubmed/23236287
http://dx.doi.org/10.1371/journal.pgen.1003065