Clostridium difficile Toxin B Causes Epithelial Cell Necrosis through an Autoprocessing-Independent Mechanism

Clostridium difficile is the most common cause of antibiotic-associated nosocomial infection in the United States. C. difficile secretes two homologous toxins, TcdA and TcdB, which are responsible for the symptoms of C. difficile associated disease. The mechanism of toxin action includes an autoproc...

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Detalles Bibliográficos
Autores principales: Chumbler, Nicole M., Farrow, Melissa A., Lapierre, Lynne A., Franklin, Jeffrey L., Haslam, David, Goldenring, James R., Lacy, D. Borden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516567/
https://www.ncbi.nlm.nih.gov/pubmed/23236283
http://dx.doi.org/10.1371/journal.ppat.1003072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516567/
https://www.ncbi.nlm.nih.gov/pubmed/23236283
http://dx.doi.org/10.1371/journal.ppat.1003072

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