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SnIPRE: Selection Inference Using a Poisson Random Effects Model

We present an approach for identifying genes under natural selection using polymorphism and divergence data from synonymous and non-synonymous sites within genes. A generalized linear mixed model is used to model the genome-wide variability among categories of mutations and estimate its functional c...

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Detalles Bibliográficos
Autores principales: Eilertson, Kirsten E., Booth, James G., Bustamante, Carlos D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516574/
https://www.ncbi.nlm.nih.gov/pubmed/23236270
http://dx.doi.org/10.1371/journal.pcbi.1002806