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A Global Comparison of the Human and T. brucei Degradomes Gives Insights about Possible Parasite Drug Targets
We performed a genome-level computational study of sequence and structure similarity, the latter using crystal structures and models, of the proteases of Homo sapiens and the human parasite Trypanosoma brucei. Using sequence and structure similarity networks to summarize the results, we constructed...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516576/ https://www.ncbi.nlm.nih.gov/pubmed/23236535 http://dx.doi.org/10.1371/journal.pntd.0001942 |