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Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection

BACKGROUND: As most cases of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) have concurrent cirrhosis, viral factors identified to be associated with HCC might be related to cirrhosis rather than HCC. METHODS: Hepatitis B virus DNA levels, genotypes and precore/basal core promoter (B...

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Detalles Bibliográficos
Autores principales: Chu, C-M, Lin, C-C, Chen, Y-C, Jeng, W-J, Lin, S-M, Liaw, Y-F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516680/
https://www.ncbi.nlm.nih.gov/pubmed/23079574
http://dx.doi.org/10.1038/bjc.2012.474