Characterization of Streptokinases from Group A Streptococci Reveals a Strong Functional Relationship That Supports the Coinheritance of Plasminogen-binding M Protein and Cluster 2b Streptokinase

Group A streptococcus (GAS) strains secrete the protein streptokinase (SK), which functions by activating host human plasminogen (hPg) to plasmin (hPm), thus providing a proteolytic framework for invasive GAS strains. The types of SK secreted by GAS have been grouped into two clusters (SK1 and SK2)...

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Detalles Bibliográficos
Autores principales: Zhang, Yueling, Liang, Zhong, Hsueh, Hsing-Tse, Ploplis, Victoria A., Castellino, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516755/
https://www.ncbi.nlm.nih.gov/pubmed/23086939
http://dx.doi.org/10.1074/jbc.M112.417808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516755/
https://www.ncbi.nlm.nih.gov/pubmed/23086939
http://dx.doi.org/10.1074/jbc.M112.417808

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