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Mannosylated Lipid Nano-emulsions Loaded with Lycorine-oleic Acid Ionic Complex for Tumor Cell-specific Delivery

This study was to prepare a mannosylated lycorine lipid nano-emulsion formulation (M-LYC-OA-LNEs) for the aim of achieving tumor targeting delivery of lycorine (LYC) . The low lipophilicity of LYC made it hard to be dispersed into lipid nano-emulsions (LNEs). In order to increase its lipophilicity,...

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Detalles Bibliográficos
Autores principales: Guo, Yangming, Liu, Xing, Sun, Xun, Zhang, Qiang, Gong, Tao, Zhang, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516834/
https://www.ncbi.nlm.nih.gov/pubmed/23227126
http://dx.doi.org/10.7150/thno.4525