Low Molecular Weight Hydroxyethyl Chitosan-Prednisolone Conjugate for Renal Targeting Therapy: Synthesis, Characterization and In Vivo Studies

To further evaluate the potential renal targeting profile of low molecular weight hydroxyethyl chitosan (LMWHC) we developed before, prednisolone (Pre) was conjugated with LMWHC by EDC/NHS chemistry to improve the therapeutic effect of glucocorticoids in vivo. The conjugate was denoted as LMWHC-Pre....

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Detalles Bibliográficos
Autores principales: He, Xia-kai, Yuan, Zhi-xiang, Wu, Xiao-juan, Xu, Chao-qun, Li, Wan-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516838/
https://www.ncbi.nlm.nih.gov/pubmed/23227122
http://dx.doi.org/10.7150/thno.3705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516838/
https://www.ncbi.nlm.nih.gov/pubmed/23227122
http://dx.doi.org/10.7150/thno.3705

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