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A Rigid Bicyclic Platform for the Generation of Conformationally Locked Neuraminidase Inhibitors
[Image: see text] Rapid mutation of the influenza virus through genetic mixing raises the prospect of new strains that are both highly transmissible and highly lethal, and which have the ability to evade both immunization strategies (through mutation of hemagglutinin) and current therapies (through...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516865/ https://www.ncbi.nlm.nih.gov/pubmed/23181823 http://dx.doi.org/10.1021/ol3027939 |