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A Common STEP in the Synaptic Pathology of Diverse Neuropsychiatric Disorders

Synaptic function is critical for proper cognition, and synaptopathologies have been implicated in diverse neuropsychiatric disorders. STriatal-Enriched protein tyrosine Phosphatase (STEP) is a brain-enriched tyrosine phosphatase that normally opposes synaptic strengthening by dephosphorylating key...

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Detalles Bibliográficos
Autores principales: Johnson, Micah A., Lombroso, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516890/
https://www.ncbi.nlm.nih.gov/pubmed/23239949