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Transforming growth factor-β suppresses metastasis in a subset of human colon carcinoma cells

BACKGROUND: TGFβ signaling has typically been associated with suppression of tumor initiation while the role it plays in metastasis is generally associated with progression of malignancy. However, we present evidence here for an anti-metastatic role of TGFβ signaling. METHODS: To test the importance...

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Detalles Bibliográficos
Autores principales: Simms, Neka A K, Rajput, Ashwani, Sharratt, Elizabeth A, Ongchin, Melanie, Teggart, Carol A, Wang, Jing, Brattain, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517326/
https://www.ncbi.nlm.nih.gov/pubmed/22672900
http://dx.doi.org/10.1186/1471-2407-12-221