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Transforming growth factor-β suppresses metastasis in a subset of human colon carcinoma cells
BACKGROUND: TGFβ signaling has typically been associated with suppression of tumor initiation while the role it plays in metastasis is generally associated with progression of malignancy. However, we present evidence here for an anti-metastatic role of TGFβ signaling. METHODS: To test the importance...
Autores principales: | Simms, Neka A K, Rajput, Ashwani, Sharratt, Elizabeth A, Ongchin, Melanie, Teggart, Carol A, Wang, Jing, Brattain, Michael G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517326/ https://www.ncbi.nlm.nih.gov/pubmed/22672900 http://dx.doi.org/10.1186/1471-2407-12-221 |
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