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Early intravenous unfractionated heparin and outcome in acute lung injury and acute respiratory distress syndrome – a retrospective propensity matched cohort study

BACKGROUND: Acute lung injury (ALI) is characterized by a pro-coagulant state. Heparin is an anticoagulant with anti-inflammatory properties. Unfractionated heparin has been found to be protective in experimental models of ALI. We hypothesized that an intravenous therapeutic dose of unfractionated h...

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Detalles Bibliográficos
Autores principales: Hofstra, Jorrit J, Vlaar, Alexander P J, Prins, David J, Koh, Gavin, Levi, Marcel, Schultz, Marcus J, Binnekade, Jan M, Juffermans, Nicole P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517343/
https://www.ncbi.nlm.nih.gov/pubmed/22894723
http://dx.doi.org/10.1186/1471-2466-12-43