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Development, screening, and analysis of DNA aptamer libraries potentially useful for diagnosis and passive immunity of arboviruses

BACKGROUND: Nucleic acid aptamers have long demonstrated the capacity to bind viral envelope proteins and to inhibit the progression of pathogenic virus infections. Here we report on initial efforts to develop and screen DNA aptamers against recombinant envelope proteins or synthetic peptides and wh...

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Detalles Bibliográficos
Autores principales: Bruno, John G, Carrillo, Maria P, Richarte, Alicia M, Phillips, Taylor, Andrews, Carrie, Lee, John S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517355/
https://www.ncbi.nlm.nih.gov/pubmed/23148669
http://dx.doi.org/10.1186/1756-0500-5-633