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Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines

BACKGROUND: Crosstalk between malignant hepatocytes and the surrounding peritumoral stroma is a key modulator of hepatocarcinogenesis and therapeutic resistance. To examine the chemotherapy resistance of these two cellular compartments in vitro, we evaluated a well-established hepatic tumor cell lin...

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Detalles Bibliográficos
Autores principales: Rangwala, Fatima, Williams, Kevin P, Smith, Ginger R, Thomas, Zainab, Allensworth, Jennifer L, Lyerly, H Kim, Diehl, Anna Mae, Morse, Michael A, Devi, Gayathri R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517386/
https://www.ncbi.nlm.nih.gov/pubmed/22963400
http://dx.doi.org/10.1186/1471-2407-12-402