Complex Interplay between the Lipin 1 and the Hepatocyte Nuclear Factor 4 α (HNF4α) Pathways to Regulate Liver Lipid Metabolism

Lipin 1 is a bifunctional protein that serves as a metabolic enzyme in the triglyceride synthesis pathway and regulates gene expression through direct protein-protein interactions with DNA-bound transcription factors in liver. Herein, we demonstrate that lipin 1 is a target gene of the hepatocyte nu...

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Detalles Bibliográficos
Autores principales: Chen, Zhouji, Gropler, Matthew C., Mitra, Mayurranjan S., Finck, Brian N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517414/
https://www.ncbi.nlm.nih.gov/pubmed/23236470
http://dx.doi.org/10.1371/journal.pone.0051320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517414/
https://www.ncbi.nlm.nih.gov/pubmed/23236470
http://dx.doi.org/10.1371/journal.pone.0051320

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