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Escherichia coli RecG functionally suppresses human Bloom syndrome phenotypes
Defects in the human BLM gene cause Bloom syndrome, notable for early development of tumors in a broad variety of tissues. On the basis of sequence similarity, BLM has been identified as one of the five human homologs of RecQ from Escherichia coli. Nevertheless, biochemical characterization of the B...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517418/ https://www.ncbi.nlm.nih.gov/pubmed/23110454 http://dx.doi.org/10.1186/1471-2199-13-33 |