Cargando…
Aquaporin 3 (AQP3) participates in the cytotoxic response to nucleoside-derived drugs
BACKGROUND: Nucleoside analogs used in the chemotherapy of solid tumors, such as the capecitabine catabolite 5(′)-deoxy-5-fluorouridine (5(′)-DFUR) trigger a transcriptomic response that involves the aquaglyceroporin aquaporin 3 along with other p53-dependent genes. Here, we examined whether up-regu...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517434/ https://www.ncbi.nlm.nih.gov/pubmed/23017148 http://dx.doi.org/10.1186/1471-2407-12-434 |