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Use of a chemically induced-colon carcinogenesis-prone Apc-mutant rat in a chemotherapeutic bioassay

BACKGROUND: Chemotherapeutic bioassay for colorectal cancer (CRC) with a rat model bearing chemically-induced CRCs plays an important role in the development of new anti-tumor drugs and regimens. Although several protocols to induce CRCs have been developed, the incidence and number of CRCs are not...

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Detalles Bibliográficos
Autores principales: Yoshimi, Kazuto, Hashimoto, Takao, Niwa, Yusuke, Hata, Kazuya, Serikawa, Tadao, Tanaka, Takuji, Kuramoto, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517449/
https://www.ncbi.nlm.nih.gov/pubmed/23031214
http://dx.doi.org/10.1186/1471-2407-12-448