The Anti-Proliferative Activity of BTG/TOB Proteins Is Mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) Deadenylase Subunits of the Ccr4-Not Complex

The human BTG/TOB protein family comprises six members (BTG1, BTG2/PC3/Tis21, BTG3/Ana, BTG4/PC3B, TOB1/Tob, and TOB2) that are characterised by a conserved BTG domain. This domain mediates interactions with the highly similar Caf1a (CNOT7) and Caf1b (CNOT8) catalytic subunits of the Ccr4-Not deaden...

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Detalles Bibliográficos
Autores principales: Doidge, Rachel, Mittal, Saloni, Aslam, Akhmed, Winkler, G. Sebastiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517456/
https://www.ncbi.nlm.nih.gov/pubmed/23236473
http://dx.doi.org/10.1371/journal.pone.0051331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517456/
https://www.ncbi.nlm.nih.gov/pubmed/23236473
http://dx.doi.org/10.1371/journal.pone.0051331

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