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Amyloid Beta Precursor Protein and Prion Protein Have a Conserved Interaction Affecting Cell Adhesion and CNS Development

Genetic and biochemical mechanisms linking onset or progression of Alzheimer Disease and prion diseases have been lacking and/or controversial, and their etiologies are often considered independent. Here we document a novel, conserved and specific genetic interaction between the proteins that underl...

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Detalles Bibliográficos
Autores principales: Kaiser, Darcy M., Acharya, Moulinath, Leighton, Patricia L. A., Wang, Hao, Daude, Nathalie, Wohlgemuth, Serene, Shi, Beipei, Allison, W. Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517466/
https://www.ncbi.nlm.nih.gov/pubmed/23236467
http://dx.doi.org/10.1371/journal.pone.0051305