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Amyloid Beta Precursor Protein and Prion Protein Have a Conserved Interaction Affecting Cell Adhesion and CNS Development
Genetic and biochemical mechanisms linking onset or progression of Alzheimer Disease and prion diseases have been lacking and/or controversial, and their etiologies are often considered independent. Here we document a novel, conserved and specific genetic interaction between the proteins that underl...
Autores principales: | Kaiser, Darcy M., Acharya, Moulinath, Leighton, Patricia L. A., Wang, Hao, Daude, Nathalie, Wohlgemuth, Serene, Shi, Beipei, Allison, W. Ted |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517466/ https://www.ncbi.nlm.nih.gov/pubmed/23236467 http://dx.doi.org/10.1371/journal.pone.0051305 |
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