Intranasal Administration of dsRNA Analog Poly(I:C) Induces Interferon-α Receptor-Dependent Accumulation of Antigen Experienced T Cells in the Airways

Polyriboinosinic-polyribocytoidylic acid (pIC), a synthetic dsRNA, acts as an adjuvant that boosts immune responses and protection. Intranasal (IN) administration of pIC has recently been used to adjuvant influenza virus vaccines; however, the effects of IN pIC administration on pulmonary T cell res...

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Detalles Bibliográficos
Autores principales: McNally, Beth, Willette, Meredith, Ye, Fang, Partida-Sanchez, Santiago, Flaño, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517467/
https://www.ncbi.nlm.nih.gov/pubmed/23236482
http://dx.doi.org/10.1371/journal.pone.0051351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517467/
https://www.ncbi.nlm.nih.gov/pubmed/23236482
http://dx.doi.org/10.1371/journal.pone.0051351

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