Gabapentin reduces CX3CL1 signaling and blocks spinal microglial activation in monoarthritic rats

BACKGROUND: Spinal glia, particularly microglia and astrocytes, are of the utmost importance in the development and maintenance of chronic pain. A recent study from our laboratory revealed that gabapentin, a recommended first-line treatment for multiple neuropathic conditions, could also efficiently...

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Detalles Bibliográficos
Autores principales: Yang, Jia-Le, Xu, Bo, Li, Shuang-Shuang, Zhang, Wei-Shi, Xu, Hua, Deng, Xiao-Ming, Zhang, Yu-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517515/
https://www.ncbi.nlm.nih.gov/pubmed/22647647
http://dx.doi.org/10.1186/1756-6606-5-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517515/
https://www.ncbi.nlm.nih.gov/pubmed/22647647
http://dx.doi.org/10.1186/1756-6606-5-18

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