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Elicitation of Both Anti HIV-1 Env Humoral and Cellular Immunities by Replicating Vaccinia Prime Sendai Virus Boost Regimen and Boosting by CD40Lm

For protection from HIV-1 infection, a vaccine should elicit both humoral and cell-mediated immune responses. A novel vaccine regimen and adjuvant that induce high levels of HIV-1 Env-specific T cell and antibody (Ab) responses was developed in this study. The prime-boost regimen that used combinati...

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Detalles Bibliográficos
Autores principales: Zhang, Xianfeng, Sobue, Tomoyoshi, Isshiki, Mao, Makino, Shun-ichi, Inoue, Makoto, Kato, Kazunori, Shioda, Tatsuo, Ohashi, Takashi, Sato, Hirotaka, Komano, Jun, Hanabusa, Hideji, Shida, Hisatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517520/
https://www.ncbi.nlm.nih.gov/pubmed/23236521
http://dx.doi.org/10.1371/journal.pone.0051633