Insights into Factorless Translational Initiation by the tRNA-Like Pseudoknot Domain of a Viral IRES

The intergenic region internal ribosome entry site (IGR IRES) of the Dicistroviridae family adopts an overlapping triple pseudoknot structure to directly recruit the 80S ribosome in the absence of initiation factors. The pseudoknot I (PKI) domain of the IRES mimics a tRNA-like codon:anticodon intera...

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Detalles Bibliográficos
Autores principales: Au, Hilda H. T., Jan, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517527/
https://www.ncbi.nlm.nih.gov/pubmed/23236506
http://dx.doi.org/10.1371/journal.pone.0051477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517527/
https://www.ncbi.nlm.nih.gov/pubmed/23236506
http://dx.doi.org/10.1371/journal.pone.0051477

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