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Insights into Factorless Translational Initiation by the tRNA-Like Pseudoknot Domain of a Viral IRES
The intergenic region internal ribosome entry site (IGR IRES) of the Dicistroviridae family adopts an overlapping triple pseudoknot structure to directly recruit the 80S ribosome in the absence of initiation factors. The pseudoknot I (PKI) domain of the IRES mimics a tRNA-like codon:anticodon intera...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517527/ https://www.ncbi.nlm.nih.gov/pubmed/23236506 http://dx.doi.org/10.1371/journal.pone.0051477 |