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Functional 3D Human Primary Hepatocyte Spheroids Made by Co-Culturing Hepatocytes from Partial Hepatectomy Specimens and Human Adipose-Derived Stem Cells

We have generated human hepatocyte spheroids with uniform size and shape by co-culturing 1∶1 mixtures of primary human hepatocytes (hHeps) from partial hepatectomy specimens and human adipose-derived stem cells (hADSCs) in concave microwells. The hADSCs in spheroids could compensate for the low viab...

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Detalles Bibliográficos
Autores principales: No, Da Yoon, Lee, Seung-A, Choi, Yoon Young, Park, DoYeun, Jang, Ju Yun, Kim, Dong-Sik, Lee, Sang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517565/
https://www.ncbi.nlm.nih.gov/pubmed/23236387
http://dx.doi.org/10.1371/journal.pone.0050723