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The Arabidopsis thaliana SERK1 Kinase Domain Spontaneously Refolds to an Active State In Vitro

Auto-phosphorylating kinase activity of plant leucine-rich-repeat receptor-like kinases (LRR-RLK's) needs to be under tight negative control to avoid unscheduled activation. One way to achieve this would be to keep these kinase domains as intrinsically disordered protein (IDP) during synthesis...

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Detalles Bibliográficos
Autores principales: aan den Toorn, Marije, Huijbers, Mieke M. E., de Vries, Sacco C., van Mierlo, Carlo P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517577/
https://www.ncbi.nlm.nih.gov/pubmed/23236403
http://dx.doi.org/10.1371/journal.pone.0050907